HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-Hydroxy-5-(methoxycarbonyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dimethyl 4-hydroxyisophthalate | HCID 80087 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 2-Hydroxy-5-(methoxycarbonyl)benzoic acid | HCID 12717060 | 98% |
Reaction Steps
A mixture of dimethyl 4-hydroxyisophthalate (10 g) and pyridine (100 ml) was heated at reflux overnight. After cooling, 6 M hydrochloric acid was added to the reaction solution. The thus-precipitated crystals were filtered, thereby giving 9.15 g of methyl 3-carboxy-4-hydroxybenzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514452B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-c3ebfcc573ec4edf9cb123fce213ca53 |
| Source note | uspto-grants-2009_04 |