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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109456Generated: October 29, 2026

4-(Tri-n-butylstannyl)pyridine → (R)-3'-[4-(4-Pyridyl)furan-2-yl]spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one

https://huagongshe.com/reaction/2109456

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Tri-n-butylstannyl)pyridineHCID 2737318—
Reactant(R)-3'-(4-Bromofuran-2-yl)spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-oneHCID 57634256—
Product(R)-3'-[4-(4-Pyridyl)furan-2-yl]spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-oneHCID 57634235—

Reaction Steps

The title compound was prepared by a method analogous to that described in Example 14 from (R)-3′-(4-bromofuran-2-yl)spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one and 4-(tri-n-butylstannyl)pyridine. The title compound (21 mg) was obtained as a pale solid, m/z (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514567B2
Source datasetuspto-grants-2009_04
ORD IDord-99b7ac8d191a46aeab88fa8b8057481d
Source noteuspto-grants-2009_04