HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Tributylstannyl)pyrazine → (R)-3'-(4-(Pyrazin-2-yl)furan-2-yl)spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Tributylstannyl)pyrazine | HCID 2737316 | — |
| Reactant | (R)-3'-(4-Bromofuran-2-yl)spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one | HCID 57634256 | — |
| Product | (R)-3'-(4-(Pyrazin-2-yl)furan-2-yl)spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one | HCID 57634230 | — |
Reaction Steps
The title compound was prepared by a method analog to that described in Example 14 from (R)-3′-(4-bromofuran-2-yl)spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one and 2-(tri-n-butylstannyl)pyrazine. The title compound (2 mg) was obtained as a pale solid, m/z 327 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07514567B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-9f7d470331b041b985a5be8a51512de8 |
| Source note | uspto-grants-2009_04 |