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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109460Generated: October 25, 2026

3-Bromofuran → (R)-3'-(Furan-3-yl)spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-one

https://huagongshe.com/reaction/2109460

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromofuranHCID 89164—
ReactantAR-R-17779HCID 5310971—
Product(R)-3'-(Furan-3-yl)spiro[1-azabicyclo[2.2.2]octan-3,5'-oxazolidin]-2'-oneHCID 57634259—

Reaction Steps

The title compound was prepared by a method analogous to that described in Preparation 3 from (S)-spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one and 3-bromofuran. The title compound (445 mg) was obtained as a pale-yellow solid, m/z 249 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514567B2
Source datasetuspto-grants-2009_04
ORD IDord-b4ce93d1aeee46f3b4f57c5f1a8eaa4e
Source noteuspto-grants-2009_04