2-(Tributylstannyl)pyridine → HCID 57634243, compound

HRID 2109471Notes

Reaction equation

HRID 2109471 reaction equation
C([Sn](CCCC)(CCCC)C1C=CC=CN=1)CCC.[N:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[C:26]1[N:27]=[C:28]([N:37]2[CH2:41][C@:40]3([CH:46]4[CH2:47][CH2:48][N:43]([CH2:44][CH2:45]4)[CH2:42]3)[O:39][C:38]2=[O:49])[S:29][C:30]=1C1C=CC=CN=1>>[N:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[C:26]1[N:27]=[C:28]([N:37]2[CH2:41][C@:40]3([CH:46]4[CH2:45][CH2:44][N:43]([CH2:48][CH2:47]4)[CH2:42]3)[O:39][C:38]2=[O:49])[S:29][CH:30]=1

Participants

3

Reactant 2

HCID 6077842-(Tributylstannyl)pyridineHCID 69053220HCID 69053220, compound

Product 1

HCID 57634243HCID 57634243, compound

Procedure

The title compound was prepared by a method analogous to that described in Example 38 using 2-(tri-n-butylstannyl)pyridine. After reverse phase HPLC and conversion to the free base, the title compound, m/z 343 (MH+) and (R)-3′-(4,5-di(2-pyridyl)thiazol-2-yl)spiro[1-azabicyclo[2.2.2]octan-3,5′-oxazolidin]-2′-one, m/e 420 (MH+).

Workup

  1. customThe title compound was prepared by a method analogous to

Sources & evidence

ORD record
ord-cd279771b92a4320804ab39ec5ac3d80
Source dataset
uspto-grants-2009_04
Patent number
US07514567B2

Reaction notes

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