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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109541Generated: October 30, 2026

Phenyl chloroformate → 2'-(Phenoxycarbonylaminomethyl)biphenyl-2-carboxylic acid (3-methylbutyl)amide

https://huagongshe.com/reaction/2109541

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl chloroformateHCID 15891—
Reactant2'-Aminomethylbiphenyl-2-carboxylic acid (3-methylbutyl)amideHCID 67316109—
Product2'-(Phenoxycarbonylaminomethyl)biphenyl-2-carboxylic acid (3-methylbutyl)amideHCID 9931732—

Reaction Steps

From 0.34.mmol of 2′-aminomethylbiphenyl-2-carboxylic acid (3-methyl-butyl)amide (precursor 5c) and phenyl chloroformate, according to the general working procedure followed by extraction with EA and purification by, flash chromatography 55 mg of 2′-(phenoxycarbonylaminomethyl)-biphenyl-2-carboxylic acid (3-methylbutyl)amide were obtained as a resin.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514582B2
Source datasetuspto-grants-2009_04
ORD IDord-8b7bd2fcc6854a9ea315e2d629513f54
Source noteuspto-grants-2009_04