4-Acetylbenzenesulfonyl chloride → HCID 9958067, compound

HRID 2109543Notes

Reaction equation

HRID 2109543 reaction equation
[CH2:1]([NH:9][C:10]([C:12]1[C:13]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[CH2:24][NH2:25])=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:11])[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[C:26]([C:29]1[CH:34]=[CH:33][C:32]([S:35](Cl)(=[O:37])=[O:36])=[CH:31][CH:30]=1)(=[O:28])[CH3:27].C(NC(C1C(C2C=CC=CC=2C(S(C2C=CC(C(=O)C)=CC=2)(=O)=O)N)=CC=CC=1)=O)CC1C=CC=CC=1>>[CH2:1]([NH:9][C:10]([C:12]1[C:13]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=2[CH2:24][NH:25][S:35]([C:32]2[CH:31]=[CH:30][C:29]([C:26](=[O:28])[CH3:27])=[CH:34][CH:33]=2)(=[O:37])=[O:36])=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:11])[CH2:2][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 3

HCID 2664184-Acetylbenzenesulfonyl chlorideHCID 155093842'-(Aminomethyl)-N-(2-phenylethyl)[1,1'-biphenyl]-2-carboxamideHCID 68974316HCID 68974316, compound

Product 1

HCID 9958067HCID 9958067, compound

Procedure

From 0.61 mmol of 2′-aminomethylbiphenyl-2carboxylic acid phenethylamide (precursor 5a) and 4-acetylphenylsulfonyl chloride, according to the general working procedure 258 mg of 2′-(4-acetylphenylsulfonyl-aminomethyl)biphenyl-2-carboxylic acid phenethylamide were obtained;

Workup

  1. customwere obtained

Sources & evidence

ORD record
ord-89a29870876548039188fdd16499724a
Source dataset
uspto-grants-2009_04
Patent number
US07514582B2

Reaction notes

Loading…