HRID2109548

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2756260

3-acetylbenzenesulfonyl Chloride

C8H7ClO3S

HCID15509385

未命名化合物

结构：CC(=O)c1cccc(S(=O)(=O)C(N)c2ccccc2-c2ccccc2C(=O)NCc2ccccc2)c1

HCID68974354

未命名化合物

PRODUCTS

生成物

结构：CC(=O)c1cccc(S(=O)(=O)NCc2ccccc2-c2ccccc2C(=O)NCc2ccccc2)c1

HCID9892111

未命名化合物

PROCEDURE

实验过程

From 0.28 mmol of 2′-aminomethylbiphenyl-2-carboxylic acid benzylamide (precursor 5b) and 3-acetylphenylsulfonyl chloride, according to the general working procedure 110 mg of 2′-(3-acetylphenylsulfonyl-aminomethyl)biphenyl-2-carboxylic acid benzylamide were obtained;

WORKUP

后处理

customwere obtained

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-33f130bbce6d43b286aaca0516ad09ad
来源数据集: uspto-grants-2009_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07514582B2
来源说明: uspto-grants-2009_04

反应 SMILES

[CH2:1]([NH:8][C:9]([C:11]1[C:12]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[CH2:23][NH2:24])=[CH:13][CH:14]=[CH:15][CH:16]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:25]([C:28]1[CH:29]=[C:30]([S:34](Cl)(=[O:36])=[O:35])[CH:31]=[CH:32][CH:33]=1)(=[O:27])[CH3:26].C(NC(C1C(C2C=CC=CC=2C(S(C2C=CC=C(C(=O)C)C=2)(=O)=O)N)=CC=CC=1)=O)C1C=CC=CC=1>>[CH2:1]([NH:8][C:9]([C:11]1[C:12]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=2[CH2:23][NH:24][S:34]([C:30]2[CH:31]=[CH:32][CH:33]=[C:28]([C:25](=[O:27])[CH3:26])[CH:29]=2)(=[O:36])=[O:35])=[CH:13][CH:14]=[CH:15][CH:16]=1)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1