N-bromobutanimide → HCID 10183261, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of N-[4-(tert-butyl)phenyl][2-(1H-indazol-6-ylamino)(3-pyridyl)]carboxamide (620 mg) (Example 8) and NBS (330 mg) in benzene (50 ml) was heated at 80° C. for 3 h. The solvent was evaporated under reduced pressure and the residue was purified by column chromatography to give the title compound. MS (ES+): 464 (M+H)+; (ES−): 462 (M−H). Calc'd. for C23H22BrN5O−463.1.

Provenance & Evidence