Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2109795Generated: October 30, 2026

tert-butyl N-(5-(tributylstannyl)-1,3-thiazol-2-yl)carbamate → tert-Butyl 5-(cinnolin-6-yl)thiazol-2-ylcarbamate

https://huagongshe.com/reaction/2109795

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N-(5-(tributylstannyl)-1,3-thiazol-2-yl)carbamateHCID 2763269—
Reactant6-BromocinnolineHCID 11229560—
Producttert-Butyl 5-(cinnolin-6-yl)thiazol-2-ylcarbamateHCID 8661378173.1%

Reaction Steps

The title compound (0.24 g, 60%) was synthesized in a manner similar to that described in Example 253 from 6-bromocinnoline (0.25 g, 1.0 mmol) and tert-butyl 5-(tributylstannyl)thiazol-2-ylcarbamate (0.90 g, 1.5 eq). LCMS (API-ES) m/z (%): 329.4 (100%, M++H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07514566B2
Source datasetuspto-grants-2009_04
ORD IDord-4b206f8d506f4479b311b5df6fc74bb7
Source noteuspto-grants-2009_04