HCID 54691386, compound → HCID 54693563, compound

HRID 2109834Notes

Reaction equation

HRID 2109834 reaction equation
FC1C=CC(CN2C[CH2:11][N:10]3[C:13](=O)[CH:14]=[C:15](O)[C:16](O)=[C:9]3C2=O)=CC=1.[Cl:23][C:24]1[CH:25]=[C:26]([CH:42]=[CH:43][C:44]=1[F:45])[CH2:27][N:28]1[CH2:33][CH2:32][N:31]2[C:34](=[O:40])[CH:35]=[C:36]([OH:39])[C:37]([OH:38])=[C:30]2[C:29]1=[O:41]>>[Cl:23][C:24]1[CH:25]=[C:26]([CH:42]=[CH:43][C:44]=1[F:45])[CH2:27][N:28]1[CH2:33][CH2:32][N:31]2[C:34](=[O:40])[C:35]([CH2:11][N:10]3[CH2:13][CH2:14][CH2:15][CH2:16][CH2:9]3)=[C:36]([OH:39])[C:37]([OH:38])=[C:30]2[C:29]1=[O:41]

Participants

3

Reactant 2

HCID 54691386HCID 54691386, compoundHCID 54723326HCID 54723326, compound

Product 1

HCID 54693563HCID 54693563, compound

Procedure

The title compound was prepared using a procedure similar to that described in Example 11, except that 2-(4-fluorobenzyl)-8,9-dihydroxy-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione was substituted with 2-(3-chloro4-fluorobenzyl)-8,9-dihydroxy-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione.

Sources & evidence

ORD record
ord-7554c13a748b44c584f13088c1831c78
Source dataset
uspto-grants-2009_04
Patent number
US07517532B2

Reaction notes

Loading…