HCID 54710325, compound → HCID 54691246, compound
Reaction equation
[F:1][C:2]1[CH:22]=[CH:21][C:5]([CH2:6][N:7]2[CH2:12][CH2:11][N:10]3[C:13](=[O:19])[CH:14]=[C:15]([OH:18])[C:16]([OH:17])=[C:9]3[C:8]2=[O:20])=[CH:4][CH:3]=1.FC1C=CC(CN2C=[CH:33][N:32]3[C:35](=O)[CH:36]=[C:37](O)[C:38](O)=[C:31]3C2=O)=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][N:7]2[CH:12]=[CH:11][N:10]3[C:13](=[O:19])[C:14]([CH2:33][N:32]4[CH2:35][CH2:36][CH2:37][CH2:38][CH2:31]4)=[C:15]([OH:18])[C:16]([OH:17])=[C:9]3[C:8]2=[O:20])=[CH:21][CH:22]=1Participants
3
Procedure
The title compound was prepared using a procedure similar to that described in Example 11, except that 2-(4-fluorobenzyl)-8,9-dihydroxy-3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-dione was substituted with 2-(4-fluorobenzyl)-8,9-dihydroxy-2H-pyrido[1,2-a]pyrazine-1,6-dione (Example 14).
Sources & evidence
- ORD record
- ord-293de82ea14248f5ad2a6c813b6e823e
- Source dataset
- uspto-grants-2009_04
- Patent number
- US07517532B2
Reaction notes
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