HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethylpiperazine → 8-Chloro-11-(3,5-dimethyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethylpiperazine | HCID 66056 | — |
| Reactant | 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one | HCID 3653116 | — |
| Product | 8-Chloro-11-(3,5-dimethyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine | HCID 135477948 | 52.8% |
Reaction Steps
8-Chloro-5,10-dihydro-dibenzo[b,e][1,4]diazepine-11-one (25 mg, 0.1 mmol) and 2,6-dimethylpiperazine (114 mg, 1.0 mmol) were reacted according to GP4 to give 18 mg of the title compound (160FE33B). MS (ESI) 341 (MH+). Purity for MH+ (UV/MS) 100/100.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07517871B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-7f02bec0fda14ed9a311f4d735aae447 |
| Source note | uspto-grants-2009_04 |