Anthranilic Acid → HCID 12434785, compound

HRID 2109897Notes

Reaction equation

HRID 2109897 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5](F)=[C:6]([N+:8]([O-])=O)[CH:7]=1.[NH2:12][C:13]1[CH:21]=[CH:20][CH:19]=[CH:18][C:14]=1[C:15](O)=[O:16]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:12][C:13]3[CH:21]=[CH:20][CH:19]=[CH:18][C:14]=3[C:15](=[O:16])[NH:8][C:6]=2[CH:7]=1

Participants

3

Reactant 2

HCID 227Anthranilic AcidHCID 27363284-Bromo-1-fluoro-2-nitrobenzene

Product 1

HCID 12434785HCID 12434785, compoundYield 31.8%

Procedure

5-Bromo-2-fluoronitrobenzene (1.6 g, 7.4 mmol) and 2-aminobenzoic acid (0.50 g, 3.6 mmol) were reacted according to GP7 to give 331 mg of the title compound (166JO31). MS (ESI) 289 (MH+). Purity for MH+ (UV) 93%.

Sources & evidence

ORD record
ord-6c74cb35cda64658b81acb1335b2d521
Source dataset
uspto-grants-2009_04
Patent number
US07517871B2

Reaction notes

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