Sodium Hydroxide → HCID 57635938, compound

Participants

Reaction Steps

To a solution of compound (16a) (102.1 mg, 0.203 mmol) in 5 mL of MeOH was added 1 M NaOH (0.41 mL, 0.407 mmol). The reaction mixture was refluxed for 1 h, and concentrated. HPLC purification gave 3-[5-(3-amino-phenylamino)-3-(4-carboxy-butyl)-pyrazolo[1,5-a]pyrimidin-7-ylamino]-benzoic acid (17a) (50 mg).

Provenance & Evidence