Aniline → 4-[(Pyridin-2-yl)sulfanyl]aniline

HRID 2110075Notes

Reaction equation

HRID 2110075 reaction equation
S1[CH:5]=[CH:4][C:3]([S:6][C:7]2[CH:13]=[CH:12][C:10]([NH2:11])=[CH:9][CH:8]=2)=C1.S1C=CC(SC2C=C[C:23]([N+:26]([O-])=O)=[CH:22]C=2)=C1.NC1C=CC=CC=1>>[N:26]1[CH:23]=[CH:22][CH:5]=[CH:4][C:3]=1[S:6][C:7]1[CH:8]=[CH:9][C:10]([NH2:11])=[CH:12][CH:13]=1

Participants

4

Reactant 3

HCID 6115AnilineHCID 23023086HCID 23023086, compoundHCID 23023091HCID 23023091, compound

Product 1

HCID 189716604-[(Pyridin-2-yl)sulfanyl]aniline

Procedure

4-(3-Thienylthio)aniline: 4-(3-Thienylthio)-1-nitrobenzene was reduced to the aniline in a manner analogous to that described in Method B1. A13j. General Method for Substituted Aniline Formation via Nitroarene Formation Through Nucleophilic Aromatic Substitution, Followed by Reduction

Sources & evidence

ORD record
ord-12c12cd7470f49bfa76d672f31b36d66
Source dataset
uspto-grants-2009_04
Patent number
US07517880B2

Reaction notes

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