Cyclopentylamine → HCID 11587409, compound

HRID 2110103Notes

Reaction equation

HRID 2110103 reaction equation
Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[C:5]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[N:6]2[CH3:11].[CH:18]1([NH2:23])[CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH:18]1([NH:23][C:2]2[N:10]=[CH:9][N:8]=[C:7]3[C:3]=2[N:4]=[C:5]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[N:6]3[CH3:11])[CH2:22][CH2:21][CH2:20][CH2:19]1

Participants

3

Reactant 2

HCID 2906CyclopentylamineHCID 11230310HCID 11230310, compound

Product 1

HCID 11587409HCID 11587409, compound

Procedure

6-chloro-9-methyl-8-phenylpurine (1.0 mmol) was added to cyclopentylamine (10 mL). The reaction mixtures were stirred at room temperature for 5 hours. After that, the solvent was evaporated and pure cyclopentyl(9-methyl-8-phenylpurin-6-yl)amine, a compound of Formula (I), was obtained after silica gel chromatography.

Workup

  1. customThe reaction mixtures
  2. customAfter that, the solvent was evaporated

Sources & evidence

ORD record
ord-19c9607b62fe45b2a3181aa04e92a930
Source dataset
uspto-grants-2009_04
Patent number
US07517888B2

Reaction notes

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