Tert-butyl 4-formylbenzoate → Tert-butyl 4-({[2-(2-{[4-(2-phenylethyl)benzyl]oxy}phenyl)ethyl]amino}-methyl)benzoate
Reaction equation
[C:1]1([CH2:7][CH2:8][C:9]2[CH:25]=[CH:24][C:12]([CH2:13][O:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[CH2:21][CH2:22][NH2:23])=[CH:11][CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:26]([C:28]1[CH:40]=[CH:39][C:31]([C:32]([O:34][C:35]([CH3:38])([CH3:37])[CH3:36])=[O:33])=[CH:30][CH:29]=1)=O>>[C:1]1([CH2:7][CH2:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:13][O:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[CH2:21][CH2:22][NH:23][CH2:26][C:28]3[CH:40]=[CH:39][C:31]([C:32]([O:34][C:35]([CH3:36])([CH3:38])[CH3:37])=[O:33])=[CH:30][CH:29]=3)=[CH:24][CH:25]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1Participants
3
Procedure
This compound was prepared analogously to Ex. I.1 from 2-(2-{[4-(2-phenylethyl)-benzyl]oxy}phenyl)ethylamine and tert-butyl 4-formylbenzoate.
Workup
- customThis compound was prepared analogously to Ex
Sources & evidence
- ORD record
- ord-a8bbe43824414abf9157e77f068dbf6e
- Source dataset
- uspto-grants-2009_04
- Patent number
- US07517896B2
Reaction notes
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