HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorophenol → HCID 21901973, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorophenol | HCID 9732 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | Methanesulfonic acid 1-[1-(4-chloro-phenyl)-cyclobutanecarbonyl]-piperidin-3-ylmethyl ester | HCID 12992442 | — |
| Reactant | HCID 21902076 | HCID 21902076 | — |
| Product | HCID 21901973 | HCID 21901973 | 57.4% |
Reaction Steps
Compound 84 was synthesized from 4-fluorophenol (0.29 g, 2.60 mmol), cesium carbonate (1.27 g, 3.89 mmol) and compound 43 (1.0 g, 2.60 mmol), using the method described for the synthesis of compound 44 to give 0.60 g of the desired product 84. C23H25ClFNO2, LRMS (m/z)=402 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07517892B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-0c83be3f40c242e1a00610353d080a18 |
| Source note | uspto-grants-2009_04 |