HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → HCID 68903051, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | HCID 68903031 | HCID 68903031 | — |
| Reactant | HCID 68903053 | HCID 68903053 | — |
| Product | HCID 68903051 | HCID 68903051 | — |
Reaction Steps
In an analogous manner to EXAMPLE 117, step 6 3-amino-1-(7-fluoro-3-methyl-1H-indol-1-yl)-1-phenylpropan-2-ol hydrochloride was prepared from (2S,3S)-3-(7-fluoro-3-methyl-1H-indol-1-yl)-3-phenylpropane-1,2-diol (EXAMPLE 179, step 4) and para-toluenesulfonic acid followed by ammonium hydroxide as a white solid. MS (ES) m/z 299.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07517899B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-f8d7660dbf9c4165b0a786c8dec7c359 |
| Source note | uspto-grants-2009_04 |