4,4-Diaminodiphenylmethane → HCID 18465586, compound

Participants

Reaction Steps

30 ml of toluene was added to 4.000 g (20.175 mmol) of 4,4-methylenedianiline, 15.839 g (161.396 mmol) of cyclohexanone, and 10.0 g of molecular sieves (4 Å). The mixture was reacted at 100° C. for 2 days. The mixture was cooled to room temperature, molecular sieves were filtered, and dried in a vacuum at 60° C. to prepare 4-(4-(cyclohexylideneamino)benzyl)-N-cyclohexylidenebenzeneamine. The obtained product was dissolved in 60 ml of methanol, 4.576 g (121.047 mmol) of sodium borohydride was added thereto, and the mixture was reacted at room temperature for 2 hours. Then, the mixture was neutralized with 80 ml of 1 N KOH. An aqueous layer was extracted twice with 60 ml of M.C, and dried with MgSO4. Then, the obtained product was recrystallized in hexane and ethylacetate. As a result, 3.765 g of white solid product (Compound 1) was obtained (Yield: 51%).

Provenance & Evidence