Sodium Hydroxide → HCID 178502624, compound

Participants

Reaction Steps

2-Hydroxy-1,4-naphthoquinone (3 g, 17 mmol) was dissolved in ethanol (30 mL) and aqueous sodium hydroxide (1N, 51 mL, 51 mmol) and treated with methoxyamine hydrochloride (2.86 g, 34 mmol) at 80° C. for 5 h. The mixture was cooled, the solvents were evaporated, and the crude mixture was acidified using 10% HCl (20 mL). The solids were filtered, rinsed with water, and dried in the vacuum to give the title compound (3.26 g, 93%).

Provenance & Evidence