HCID 136396872, compound → HCID 136396995, compound

Participants

Reaction Steps

To a solution of Example 83A (905 mg, 1.6 mmol) in CH3CN (72 mL) and H2O (5 mL) was added molybdenum hexacarbonyl (293 mg, 1.1 mmol) and the solution was refluxed for 2 hours, cooled to room temperature, solvent removed in vacuo and the crude residue purified by column chromatography on silica gel (2% methanol/chloroform) to give the title compound as a colorless solid (670 mg, 78%): 1H NMR (d6-DMSO) δ 14.34 (s, 1H), 9.64 (s, 1H), 8.59 (br s, 2H), 8.13, 8.11 (d, 1H), 7.93 (s, 1H), 7.69-7.45 (m, 4H), 7.27, 7.24 (d, 1H), 2.08-1.95 (m, 1H), 1.92-1.80 (m, 1H), 1.30-0.99 (m, 4H), 0.54-0.46 (m, 1H), 1.50 (s, 9H), 1.45-1.23 (m, 1H), 1.18-0.96 (m, 1H), 0.92-0.62 (m, 7H); MS (ESI) m/z 541 (M+H+).

Provenance & Evidence