Chloroform → HCID 86607420, compound

Participants

Reaction Conditions

Reaction Steps

1-(2-Chlorophenyl)ethyl[3-(4-(2-chloroethyl)phenyl)isoxazolyl]carbamate (481 mg, 1.19 mmol) was dissolved in chloroform (10 ml), methyl thioglycolate (379 mg, 3.57 mmol), and triethylamine (600 mg, 5.93 mmol) were added, and the mixture was stirred overnight at 50° C. The solvent was evaporated under reduced pressure and the residue was purified by silica gel chromatography (hexane:ethyl acetate=4:1) to give the title compound (190 mg, 34%).

Provenance & Evidence