反应详情

According to methods similar to those of Step 5 and Step 6 of Example 19 using 3-(4-iodophenyl)isoxazole-4-carboxylic acid and (R)-2-chloro-α-methylbenzyl alcohol, methyl 5-(4-{4-[(1R)-1-(2-chlorophenyl)ethoxycarbonylamino]-3-isoxazolyl}phenyl)-4-pentenoate was synthesized, which was reacted in the same manner as in Example 2 to give the title compound.

1. customwas synthesized
2. customwhich was reacted in the same manner as in Example 2