Cyclopentylamine → HCID 57635054, compound

HRID 2111244Notes

Reaction equation

HRID 2111244 reaction equation
[CH:1]1([NH2:6])[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:7]=[C:8]1[CH2:12][CH2:11][O:10][C:9]1=[O:13]>>[CH:1]1([NH:6][CH2:7][CH:8]2[CH2:12][CH2:11][O:10][C:9]2=[O:13])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 2906CyclopentylamineHCID 68352alpha-Methylene butyrolactone

Product 1

HCID 57635054HCID 57635054, compoundYield 88.1%

Procedure

A mixture of 4.44 g (0.0521 mole) of cyclopentylamine and 5.12 g (0.0521 mole) of dihydro-3-methylene-(3H)-furanone was stirred at room temperature for 40 minutes and then distilled under vacuum to give 8.41 g of (rac)-3-[(cyclopentylamino)methyl]dihydro-2(3H)-furanone, b.p. 120-128 degrees, 0.3 mm Hg.

Workup

  1. distillationdistilled under vacuum

Sources & evidence

ORD record
ord-1a9b065d7ba545528a53a3a4b1030be8
Source dataset
uspto-grants-2009_04
Patent number
US07517873B2

Reaction notes

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