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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2111565Generated: October 31, 2026

Trifluoroacetic acid → HCID 46318272, compound

https://huagongshe.com/reaction/2111565

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 46318296HCID 46318296—
SolventDichloromethaneHCID 6344—
ProductHCID 46318272HCID 46318272—

Reaction Steps

(tert-Butoxy)-N-[1-(pyrrolidinylcarbonyl)(4-piperidyl)]carboxamide (2.0 g, 6.73 mmol) was dissolved in 40 mL dichloromethane and trifluoroacetic acid (15 mL, 201.94 mmol) were added. The reaction mixture was stirred for 4 hours. The solvent was evaporated to give the product as a light brown semi-solid, which was used directly for the next step. (2.09 g, 6.73 mmol, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07521446B2
Source datasetuspto-grants-2009_04
ORD IDord-0f657b362f6d4fa3aabe518a6a38785b
Source noteuspto-grants-2009_04