HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2111611Generated: October 26, 2026
Mesitene lactone → 4,6-Dimethylisobenzofuran-1,3-dione
https://huagongshe.com/reaction/2111611
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Mesitene lactone | HCID 12662 | — |
| Reactant | Chloromaleic anhydride | HCID 66772 | — |
| Product | 4,6-Dimethylisobenzofuran-1,3-dione | HCID 14574733 | 63.8% |
Reaction Steps
4,6-dimethyl-2-pyrone (1.0 g, 8.1 mmol) and 2-chloromaleic anhydride (1.5 g, 11 mmol) were stirred with heating at 160° C. for 3 hrs, and the precipitated crystals were purified by silica gel chromatography (chloroform) to give 0.91 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07521451B2 |
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| Source dataset | uspto-grants-2009_04 |
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| ORD ID | ord-d24c354f98eb4d30a596ec06a0799689 |
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| Source note | uspto-grants-2009_04 |
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