Maleic Anhydride → 5,6-Dimethyl-3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione

Participants

Reaction Conditions

Reaction Steps

To a solution of maleic anhydride (5.4 g, 55 mmol) in benzene (50 ml) was added dropwise 2,3-dimethyl-1,3-butadiene (6.3 ml, 55 mmol), and stirred overnight at 25° C. After separating the insoluble materials by filtration, the filtrate was concentrated under reduced pressure to give 9.5 g of 5,6-dimethyl-3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione.

Provenance & Evidence