反应详情

温度

25 °C

To a solution of the product of above-mentioned (10-b) (88 mg, 0.27 mmol) in ethanol (10 ml) was added 18 mg of 10% palladium on carbon, and stirred vigorously under a hydrogen atmosphere at 25° C. for 2 hrs. The reaction solution was filtered, and the filtrate was concentrated under reduced pressure, and the residue was purified by silica gel chromatography (chloroform:acetone=5:1) to give 20 mg of the title compound.

1. filtrationThe reaction solution was filtered
2. concentrationthe filtrate was concentrated under reduced pressure
3. customthe residue was purified by silica gel chromatography (chloroform:acetone=5:1)