Sulfuric Acid → HCID 178448881, compound

HRID 2111664Notes

Reaction equation

HRID 2111664 reaction equation
[S:1](=[O:5])(=[O:4])([OH:3])[OH:2].[CH2:6]([NH:10][C:11]1[N:19]=[C:18]2[C:14]([N:15]=[C:16]([OH:28])[N:17]2[CH2:20][C:21]2[CH:22]=[N:23][C:24]([CH3:27])=[CH:25][CH:26]=2)=[C:13]([NH2:29])[N:12]=1)[CH2:7][CH2:8][CH3:9]>CO>[S:1]([OH:5])([OH:4])(=[O:3])=[O:2].[CH2:6]([NH:10][C:11]1[N:19]=[C:18]2[C:14]([N:15]=[C:16]([OH:28])[N:17]2[CH2:20][C:21]2[CH:22]=[N:23][C:24]([CH3:27])=[CH:25][CH:26]=2)=[C:13]([NH2:29])[N:12]=1)[CH2:7][CH2:8][CH3:9]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 178448880HCID 178448880, compound

Product 1

HCID 178448881HCID 178448881, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

0.5N sulfuric acid (30.8 ml) was added to a methanol solution (520 ml) of the compound of Example 27 (2.52 g, 7.70 mmol), and the precipitated crystal was collected by filtration. Thus, the title compound was obtained.

Workup

  1. filtrationthe precipitated crystal was collected by filtration

Sources & evidence

ORD record
ord-a840ef39bf044a14ac8eeda2287aeb42
Source dataset
uspto-grants-2009_04
Patent number
US07521454B2

Reaction notes

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