Ammonium Chloride → HCID 23151228, compound

Participants

Reaction Steps

2-bromo-1-(3-chloropropoxy)-4-nitrobenzene (1.3 g), ammonium chloride (1.3 g) and iron (1.3 g) were added to a mixed solvent of methanol (8 mL) and distilled water (4 mL), and the mixture was heated under reflux for 2 hours. The reaction mixture was filtered through cerite, and the filtrate was concentrated. The residue was dissolved in ethyl acetate, and washed with distilled water and saturated brine. The organic phase was dried with anhydrous sodium sulfate, concentrated and dried to obtain the target substance (0.92 g).

Provenance & Evidence