1-Benzyl-3-pyrrolidinone → N-benzyl-3-pyrrolidinol
Reaction equation
[CH2:1]([N:8]1[CH2:12][CH2:11][C:10](=[O:13])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[BH4-].[Na+]>>[CH2:1]([N:8]1[CH2:12][CH2:11][CH:10]([OH:13])[CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
1-benzyl-3-pyrrolidinone was reduced with sodium borohydride according to Example 117-(1), and the target compound was obtained.
Workup
- customthe target compound was obtained
Sources & evidence
- ORD record
- ord-777ba3de9f77495e997b3f5f946bae13
- Source dataset
- uspto-grants-2009_04
- Patent number
- US07521455B2
Reaction notes
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