HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxy-4-nitrobenzimidamide → 2-[2-(4-Amino-3-methoxy-phenyl)-thiazole-5-yl]-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxy-4-nitrobenzimidamide | HCID 18727706 | — |
| Reactant | 4-Amino-3-methoxy-thiobenzamide | HCID 82668898 | — |
| Product | 2-[2-(4-Amino-3-methoxy-phenyl)-thiazole-5-yl]-ethanol | HCID 57639861 | — |
Reaction Steps
2-[2-(4-amino-3-methoxy-phenyl)-thiazole-5-yl]-ethanol is prepared analogously to the processes described above. For the cyclisation, 4-amino-3-methoxy-thiobenzamide is used (analogously to J. Am. Soc. 82, 2656, 1960) instead of 3-methoxy-4-nitro-benzamidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07521457B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-ed472c58402942e9b10c81fe37385214 |
| Source note | uspto-grants-2009_04 |