Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2112388Generated: October 26, 2026

Sodium Methoxide → 2-(3H-imidazo[4,5-b]pyridin-3-ylmethoxy)-ethanol

https://huagongshe.com/reaction/2112388

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium MethoxideHCID 10942334—
Reactantacetic acid 2-(3H-imidazo[4,5-b]pyridin-3-ylmethoxy)-ethyl esterHCID 68879998—
SolventMethanolHCID 887—
Product2-(3H-imidazo[4,5-b]pyridin-3-ylmethoxy)-ethanolHCID 1446404799%

Reaction Steps

0.79 g (3.36 mmol) acetic acid 2-(3H-imidazo[4,5-b]pyridin-3-ylmethoxy)-ethyl ester were dissolved in 10 ml methanol and 10 mg (1.85 mmol) sodium methoxide were added. The mixture was stirred at room temperature for 3 hours. The orange mixture was concentrated in vacuo to afford 0.64 g (99%) of crude product. MS (EI): 193.2, 163.2, 148.2, 133.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07524823B2
Source datasetuspto-grants-2009_04
ORD IDord-6a882374f2714fc8a71d2ed4c286d4ab
Source noteuspto-grants-2009_04