Potassium ethanethioate → HCID 86609192, compound

Participants

Reaction Steps

A solution of 0.41 g (2.0 mmol) 6-(3-chloro-propyl)-quinoline and 287 mg (2.5 mmol) potassium thioacetate in 8 ml acetone was heated to reflux for 8 hours. The mixture was concentrated in vacuo. The crude product was purified by flash chromatography (silica gel, gradient of 0 to 2% methanol in DCM) to afford 353 mg (71%) of dark orange oil. MS(ISP): 246.3 [MH]+

Provenance & Evidence