HCID 86612905, compound → HCID 178434909, compound

Participants

Reaction Steps

To a solution of the title product from Example 1 (10 mg, 0.030 mmol) in ethanol (20 mL) was added 1-2 mg PtO2. The reaction vessel was flushed with H2 gas and held at 1 atm of H2 via balloon for 24 hours. The platinum catalyst was filtered and the filtrate was concentrated and the crude product was purified on silica gel methanol/methylene chloride (1:20) as the eluent to afford 4.0 mg of the title compound;

Provenance & Evidence