(1,1'-Biphenyl)-4-sulphonyl chloride → 1-([1,1'-Biphenyl]-4-yl-sulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride

Participants

Role	Name	HCID	Charge
Reactant	(1,1'-Biphenyl)-4-sulphonyl chloride	HCID 74192	—
Reactant	tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate	HCID 22015386	—
Product	1-([1,1'-Biphenyl]-4-yl-sulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride	HCID 10226082	—

Reaction Steps

The title compound was prepared from 4-(4-boc-piperazinyl)-indole and 1,1′-biphenyl-4-ylsulfonyl chloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.26 (br, 1H), 8.04 (m, 2H), 7.88 (m, 3H), 7.67 (m, 3H), 7.46 (m, 3H), 7.27 (t, J=8 Hz, 1H), 6.96 (d, J=5 Hz, 1H), 6.80 (d, J=8 Hz, H), 3.25 (m 8H); MS (ESI+) for m/z 418 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07524839B2
Source dataset	uspto-grants-2009_04
ORD ID	ord-c88a4e245ec34de99884131d7535d938
Source note	uspto-grants-2009_04