3,4-Dimethoxybenzenesulfonyl chloride → 1-[(3,4-Dimethoxyphenyl)sulfonyl]-4-(1-piperazinyl)-1H-indole Hydrochloride

Participants

Role	Name	HCID	Charge
Reactant	3,4-Dimethoxybenzenesulfonyl chloride	HCID 2734183	—
Reactant	tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate	HCID 22015386	—
Product	1-[(3,4-Dimethoxyphenyl)sulfonyl]-4-(1-piperazinyl)-1H-indole Hydrochloride	HCID 10203482	—

Reaction Steps

The title compound was prepared from 4-(4-boc-piperazinyl)-indole and 3,4-dimethoxyphenylsulfonyl chloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.00 (br, 1H), 7.82 (d, J=5 Hz, 1H), 7.66 (d, J=8 Hz, 1H), 7.57 (m, 1H), 7.40 (d, J=3 Hz, 1H), 7.24 (t, J=8 Hz, 1H), 7.10 (d, J=8 Hz, 1H), 6.90 (d, J=5 Hz, 1H), 6.78 (d, J=8 Hz, 1H), 3.78 (s, 6H), 3.24 (m, 8H); MS (ESI+) for m/z 402 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07524839B2
Source dataset	uspto-grants-2009_04
ORD ID	ord-61bc9187d1184d6d84496a860ca1e9e6
Source note	uspto-grants-2009_04