HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine-3-sulfonyl chloride → 4-(1-Piperazinyl)-1-(3-pyridinylsulfonyl)-1H-indole Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine-3-sulfonyl chloride | HCID 3164136 | — |
| Reactant | tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate | HCID 22015386 | — |
| Product | 4-(1-Piperazinyl)-1-(3-pyridinylsulfonyl)-1H-indole Hydrochloride | HCID 22015331 | — |
Reaction Steps
The title compound was prepared from 4-(4-boc-piperazinyl)-indole and 3-pyridinylsulfonyl chloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.37 (br, 1H), 9.18 (d, J=3 Hz, 1H), 8.86 (d, J=5 Hz, 1H), 8.39 (d, J=8 Hz, 1H), 7.85 (d, J=3 Hz, 1H), 7.70-7.60 (m, 2H), 7.27 (t, J=8 Hz, 4H), 7.00 (d, J=3 Hz, 1H), 6.82 (d, J=8 Hz, 1H), 3.24 (m, 8H); MS (ESI+) for m/z 343 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07524839B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-a7676c7af9104a90af2e59f7707df19e |
| Source note | uspto-grants-2009_04 |