2-Methanesulfonylbenzene-1-sulfonyl chloride → Methyl 2-{[4-(1-piperazinyl)-1H-indol-1-yl]sulfonyl}phenyl Sulfone Hydrochloride

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-Methanesulfonylbenzene-1-sulfonyl chloride	HCID 2735178	—
Edukt	tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate	HCID 22015386	—
Produkt	Methyl 2-{[4-(1-piperazinyl)-1H-indol-1-yl]sulfonyl}phenyl Sulfone Hydrochloride	HCID 10139159	—

Reaktionsschritte

The title compound was prepared from 4-(4-boc-piperazinyl)-indole and 2-methylsulfonyl-phenylsulfonyl chloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.22 (br, 1H), 8.29 (d, J=8 Hz, 1H), 7.99 (t, J=8 Hz, 1H), 7.90-7.80 (m, 2H), 7.43 (d, J=8 Hz, 1H), 7.30-7.15 (m, 2H), 7.04 (d, J=3 Hz, 1H), 6.85 (d, J=8 Hz, 1H), 3.56 (s, 3H), 3.29 (m, 8H); MS (ESI+) for m/z 420 (M+H)+.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07524839B2
Quelldatensatz	uspto-grants-2009_04
ORD ID	ord-a2f3ec69f3e4460e8a095eed1fb034de
Quellennotiz	uspto-grants-2009_04