HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine → 5-(2-chlorophenyl)-8-ethoxy-7-fluoro-3-methyl-1,2-dihydropyrazolo[3,4-b][1,4]benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 1,1-Dimethoxyethyl(dimethyl)amine | HCID 87835 | — |
| Reactant | 5-(2-chlorophenyl)-1,3-dihydro-8-ethoxy-7-fluoro-2H-1,4-benzodiazepin-2-thione | HCID 57642326 | — |
| Product | 5-(2-chlorophenyl)-8-ethoxy-7-fluoro-3-methyl-1,2-dihydropyrazolo[3,4-b][1,4]benzodiazepine | HCID 178465777 | — |
Reaction Steps
5-(2-chlorophenyl)-1,2-dihydro-7-fluoro-8-ethoxy-3-methyl-pyrazolo[3,4-b][1,4]benzodiazepine (IVg) was prepared by reacting 0.0016 moles of 5-(2-chlorophenyl)-1,3-dihydro-8-ethoxy-7-fluoro-2H-1,4-benzodiazepin-2-thione (IIg) with 1,1-dimethoxy-N,N-dimethyl-ethanamine and then hydrazine in a manner analogous to Example 55. MH+/Z=371.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07524840B2 |
| Source dataset | uspto-grants-2009_04 |
| ORD ID | ord-80fe3ee4c3614cd3a4c162c6e519f296 |
| Source note | uspto-grants-2009_04 |