反应详情

5-(2-chlorophenyl)-1,2-dihydro-7,8-dimethoxy-3-methyl-pyrazolo[3,4-b][1,4]benzodiazepine (IVx) was prepared by reacting 0.00093 moles of (2-amino-4,5-dimethoxyphenyl)(2-chlorophenyl)-methanone (Xx) with 4-amino-5-chloro-3-methyl-1-(2-propenyl)-1H-pyrazole (XIII), and subsequent dealkylation of the intermediate, 5-(2-chlorophenyl)-1,2-dihydro-7,8-dimethoxy-3-methyl-1-(2-propenyl)-pyrazolo[3,4-b][1,4]benzodiazepine (XIVx) with diisobutylaluminum hydride in a manner analogous to Example 72. MH+/Z=369.