Diisobutylaluminumhydride → HCID 178486421, compound

Participants

Reaction Steps

5-(2-chlorophenyl)-1,2-dihydro-7-methoxy-3-methyl-8-trifluoromethyl-pyrazolo[3,4-b][1,4]benzodiazepine (IVee) was prepared by reacting 0.0023 moles of (2-amino-5-methoxy-4-trifluoromethylphenyl)-(2-chlorophenyl)-methanone (Xee) with 4-amino-5-chloro-3-methyl-1-(2-propenyl)-1H-pyrazole (XIII), and subsequent dealkylation of the intermediate, 5-(2-chlorophenyl)-1,2-dihydro-7-methoxy-3-methyl-1-(2-propenyl)-8-trifluoromethyl-pyrazolo[3,4-b][1,4]benzodiazepine (XIVee) with diisobutylaluminum hydride in a manner analogous to Example 72. MH+/Z=407.

Provenance & Evidence