Diisobutylaluminumhydride → HCID 178421674, compound

Participants

Reaction Steps

8-chloro-5-(2-chlorophenyl)-1,2-dihydro-3,7-dimethyl-pyrazolo[3,4-b][1,4]benzodiazepine (IVhh) was prepared by reacting 0.0023 moles of (2-amino-4-chloro-5-methylphenyl)-(2-chlorophenyl)-methanone (Xhh) with 4-amino-5-chloro-3-methyl-1-(2-propenyl)-1H-pyrazole (XIII), and subsequent dealkylation of the intermediate, 8-chloro-5-(2-chlorophenyl)-1,2-dihydro-3,7-dimethyl-1-(2-propenyl)-pyrazolo[3,4-b][1,4]benzodiazepine (XIVhh) with diisobutylaluminum hydride in a manner analogous to Example 72. MH+/Z=357.

Provenance & Evidence