Diisobutylaluminumhydride → HCID 178486549, compound

Participants

Reaction Steps

5-(2-chlorophenyl)-1,2-dihydro-7-methoxy-8-(1-methylethoxy)-3-methyl-pyrazolo[3,4-b][1,4]benzodiazepine (IVii) was prepared by reacting 0.0023 moles of (2-amino-5-methoxy-4-(1-methylethoxy)phenyl)-(2-chlorophenyl)-methanone (Xii) with 4-amino-5-chloro-3-methyl-1-(2-propenyl)-1H-pyrazole (XIII), and subsequent dealkylation of the intermediate, 5-(2-chlorophenyl)-1,2-dihydro-7-methoxy-8-(1-methylethoxy)-3-methyl-1-(2-propenyl)-pyrazolo[3,4-b][1,4]benzodiazepine (XIVii) with diisobutylaluminum hydride in a manner analogous to Example 72. MH+/Z=397.

Provenance & Evidence