Diisobutylaluminumhydride → HCID 178496068, compound

Participants

Reaction Steps

5-(2-chlorophenyl)-1,2-dihydro-8-methoxy-7-methoxyethoxy-3-methyl-pyrazolo[3,4-b][1,4]benzodiazepine (IVkk) was prepared by reacting 0.0014 moles of (2-amino-4-methoxy-5-(2-methoxyethoxy)phenyl)-(2-chlorophenyl)-methanone (Xkk) with 4-amino-5-chloro-3-methyl-1-(2-propenyl)-1H-pyrazole (XIII), and subsequent dealkylation of the intermediate, 5-(2-chlorophenyl)-1,2-dihydro-8-methoxy-7-methoxyethoxy-3-methyl-1-(2-propenyl)-pyrazolo[3,4-b][1,4]benzodiazepine (XIVkk) with diisobutylaluminum hydride in a manner analogous to Example 72. MH+/Z=413.

Provenance & Evidence