Hydrazine → HCID 178486434, compound

Participants

Reaction Steps

5-(2-chlorophenyl)-1,2-dihydro-7-cyano-8-methoxy-pyrazolo[3,4-b][1,4]benzodiazepine (XXIIb) was prepared by reacting 0.00096 moles of 5-(2-chlorophenyl)-7-cyano-1,3-dihydro-8-methoxy-2H-1,4-benzodiazepin-2-thione (IIb) with 1,1-diethoxy-N,N-dimethyl-methanamine and then hydrazine in a manner analogous to the example above. Recrystallization from ethyl acetate provided 5-(2-chlorophenyl)-1,2-dihydro-7-cyano-8-methoxy-pyrazolo[3,4-b][1,4]benzodiazepine (XXIIb) as a light red solid, mp 288-290° C.

Provenance & Evidence