HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2112577Generated: November 4, 2026
Chlorosuccinimide → HCID 178478425, compound
https://huagongshe.com/reaction/2112577
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chlorosuccinimide | HCID 31398 | — |
| Reactant | 1H-pyrazolo(3,4-b)pyridine | HCID 2755850 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178478425 | HCID 178478425 | — |
Reaction Steps
1H-pyrazolo[3,4-b]pyridine (89 mg) and N-chlorosuccinimide (220 mg) were combined in CH2Cl2 (4 mL) and heated at 45° C. for 16 hr, then cooled to room temperature. The resultant mixture was purified by flash chromatography (silica gel, 50% hexane/ethyl acetate) to afford 3-chloro-1H-pyrazolo[3,4-b]pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07524845B2 |
|---|
| Source dataset | uspto-grants-2009_04 |
|---|
| ORD ID | ord-213d2d8f001a469a9343ad58206c1da5 |
|---|
| Source note | uspto-grants-2009_04 |
|---|
