methyl((1-methyl-1H-indol-2-yl)methyl)amine → 1-Methyl-2-(methylamino methyl)-6-methoxy-1H-indole

HRID 2112676Notes

Reaction equation

HRID 2112676 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]1[CH2:11][NH:12][CH3:13].CN[C:16](C1N(C)C2C(C=1)=CC=CC=2)=[O:17]>>[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([O:17][CH3:16])[CH:9]=2)[CH:4]=[C:3]1[CH2:11][NH:12][CH3:13]

Participants

3

Reactant 2

HCID 11401058methyl((1-methyl-1H-indol-2-yl)methyl)amineHCID 12303315N,1-dimethylindole-2-carboxamide

Product 1

HCID 225937481-Methyl-2-(methylamino methyl)-6-methoxy-1H-indoleYield 76%

Procedure

According to the procedure of Preparation 1 (c), except substituting N,1-dimethyl-6-methoxy-1H-indole-2-carboxamide for N,1-dimethyl-1H-indole-2-carboxamide, the title compound (76%) was prepared as a light gray solid: MS (ES) m/e 205.2 (M+H)+, 409.4 (2M+H)+.

Sources & evidence

ORD record
ord-abc682e0de4249fc98f417909702381b
Source dataset
uspto-grants-2009_04
Patent number
US07524843B2

Reaction notes

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